Monoclonal Antibody anti-Domoic Acid



Domoic Acid (DA), the neurotoxin that causes amnesic shellfish poisoning (ASP). The toxin is produced by marine diatoms which are members of the genus Pseudo-nitzschia.
Both shellfish and fish can accumulate this toxin without apparent ill effects; however, in humans the toxin crosses into the brain and interferes with nerve
signal transmission.

ASP symptoms include vomiting, nausea, diarrhea and abdominal cramps within 24 hours of ingestion. In more severe cases, neurological symptoms like headache, dizziness, confusion, disorientation, loss of short-term memory, motor weakness, seizures, profuse respiratory secretions, cardiac arrhythmias, coma and possibly death.

Monoclonal Antibody: anti-Domoic Acid

Immunogen: Domoic Acid-KLH (carrier)

Host: mouse

Clone: K3 P2 G4

Size: 0.1, 1 and 10 mg/vial

Source: cell culture

Isotype: IgG2a-kappa

Specificity: Domoic Acid.

Buffer: phosphate buffer saline 10 mM, NaCl 150 mM, sodium azide 0,099%



Protein concentration: Lot specific. 5-10 mg/ml

Purity: > 90 %

Lot Specifications:

1- Concentration: lot specific

2- Total quantity per aliquot: 0.1-10 mg

3-Total volume for aliquot: 0,5-2 ml

4-Storage: store at 4 ºC for short term storage. Aliquot and store at -20ºC for long term storage. Avoid repeated freeze-thaw cycles.

5- Applications: IHC, ELISA,WB, colloidal micro or
nanoparticles (gold, latex, …) coating.

6- Observations:

1- this product contains sodium azide as preservative.

2-the optimal concentration must be established by the end user












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